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Spermatogenesis - Developmental Biology - An Overview

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Spermatogenesis - Developmental Biology - An Overview Abstract Spermatogenesis is the process in which spematozoa are produced from male primordial germ cells by way of mitosis and meiosis. The initial cells in this pathway are called spematogonia, which yield primary spermatocytes by mitosis. The primary spermatocyte divides meiotically into two secondary spermatocytes; each secondary spermatocyte then completes meiosis as it divides into two spermatids. These develop into mature spermatozoa, also known as sperm cells. Thus, the primary spermatocyte gives rise to two cells, the secondary spermatocytes, and the two secondary spermatocytes by their subdivision produce four spermatozoa. Spermatozoa are the mature male gametes in many sexually reproducing organisms. Thus, spermatogenesis is the male version of gametogenesis. In mammals it occurs in the male testes and epididymis in a stepwise fashion. Spermatogenesis is highly dependent upon optimal conditions for the process to occur c…