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Possible Effects of Maternal Behaviour on Foetal Development

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Possible Effects of Maternal Behaviour on Foetal Development Abstract Nutrition is the major intrauterine environmental factor that alters expression of the fetal genome and may have lifelong consequences. Namely, alterations in fetal nutrition and endocrine status may result in developmental adaptations that permanently change the structure, physiology, and metabolism of the offspring, thereby predisposing individuals to metabolic, endocrine, and cardiovascular diseases in adult life. Animal studies show that both maternal under nutrition and over nutrition reduce placental-fetal blood flows and stunt fetal growth. Impaired placental syntheses of nitric oxide (a major vasodilator and angiogenesis factor) and polyamines (key regulators of DNA and protein synthesis) may provide a unified explanation for intrauterine growth retardation in response to the 2 extremes of nutritional problems with the same pregnancy outcome. There is growing evidence that maternal nutritional status can al…

Detailed Study on Infertility its Causes and Treatment

Detailed Study on Infertility its Causes and Treatment Abstract Infertility is the inability of a person, animal or plant to reproduce by natural means. It is usually not the natural state of a healthy adult organism, except notably among certain eusocial species (mostly haplodiploid insects). In humans, infertility may describe a woman who is unable to conceive as well as being unable to carry a pregnancy to full term. There are many biological and other causes of infertility, including some that medical intervention can treat. Infertility rates have increased by 4% since the 1980s, mostly from problems with fecundity due to an increase in age. About 40% of the issues involved with infertility are due to the man, another 40% due to the woman, and 20% result from complications with both partners. Women who are fertile experience a natural period of fertility before and during ovulation, and they are naturally infertile during the rest of the menstrual cycle. Fertility awareness metho…

Spermatogenesis - Developmental Biology - An Overview

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Spermatogenesis - Developmental Biology - An Overview Abstract Spermatogenesis is the process in which spematozoa are produced from male primordial germ cells by way of mitosis and meiosis. The initial cells in this pathway are called spematogonia, which yield primary spermatocytes by mitosis. The primary spermatocyte divides meiotically into two secondary spermatocytes; each secondary spermatocyte then completes meiosis as it divides into two spermatids. These develop into mature spermatozoa, also known as sperm cells. Thus, the primary spermatocyte gives rise to two cells, the secondary spermatocytes, and the two secondary spermatocytes by their subdivision produce four spermatozoa. Spermatozoa are the mature male gametes in many sexually reproducing organisms. Thus, spermatogenesis is the male version of gametogenesis. In mammals it occurs in the male testes and epididymis in a stepwise fashion. Spermatogenesis is highly dependent upon optimal conditions for the process to occur c…